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Center for International Blood and Marrow Transplant Research

IB21-01

Main Content

Effect of HLA evolutionary divergence on survival and relapse following allogeneic hematopoietic cell transplant.

Study #: IB21-01

Study Status: Published

Presentation(s)

2023, ASH (Poster)
2023, Tandem (Poster)

Higher HLA-DRB1 evolutionary divergence (HED) is associated with reduced relapse and improved survival after matched unrelated hematopoietic cell transplantation.

Citation

Saultz JN, Bolon YT, Wang T, Spellman SR, Lee SJ, He M, Camacho-Bydume C, Krishna C, Chowell D, Shaffer BC, Hsu K, Paczesny S, Gadalla SM, Marsh SGE, Betts BC, Arrieta-Bolaños E.

Transplantation and Cellular Therapy. 2025, Dec 13: S2666-6367(25): S2666-6367(25):02611-9. doi: 10.1016/j.jtct.2025.12.949. Epub 2025, Dec 13. PMCID:.

PubMed

PMID: 41397550

Abstract