Skip to Content

Biospecimen Inventories

Main Content

Sample Types and Inventory Summary

The Research Sample Repository contains approximately 3 million sample aliquots from more than 60,000 first allogeneic related and unrelated transplant recipient/donor (or cord blood) pairs with complete, validated clinical outcome data from CIBMTR's Observational Database. The majority of the paired samples have complete high-resolution data available for HLA-A, B, C, DRB1/3/4/5, DQ and DP loci.

Sample Types

Samples in the Research Sample Repository are stored as:

  • Whole blood
  • Cryopreserved whole blood
  • Plasma
  • Blood spotted on filter paper
  • Peripheral blood mononuclear cells (PBMC) viable and non-viable
  • B-Lymphoblastoid cell lines (B-LCL) viable and non-viable
  • Granulocytes
  • Serum
  • DNA
  • Whole genome amplified DNA

Available sample types vary by sample source and year of collection. Sample sources include: Adult and pediatric related/unrelated donors, cord blood and transplant recipients. Samples from recipients are drawn before the patient’s conditioning regimen begins. Prior to January 1, 2000, 100-day post-transplant samples were also drawn.

Research Sample Repository as of April 2023  
Number of unrelated Donor/Recipient pairs 47,911
Number of unrelated Cord blood/Recipient pairs* 6,314
Number of unique unrelated Donor ID 85,745
Number of unique unrelated Recipient ID 82,070
Number of unique Cord ID 13,853
Number of unique related Donor ID 14,283
Number of unique related Recipient ID 14,908
Number of related Donor/Recipient Pairs 12,454

*Pair counts include incomplete multi-cord pairs with recipient and at least one cord sample available.

View a detailed summary of the available recipient and/or donor samples from first transplants, which includes information about the sample inventory by variable, including: age, gender, high-resolution typing, disease status, graft type, conditioning regimen, GVHD prophylaxis, and more: Repository Sample Inventory (PDF).

More information

For information about the availability of sample types or specific inventory queries, contact research-repos@nmdp.org.