VOD Risk Calculator

Hands Holding Liver Graphic

Veno-occlusive disease of the liver (VOD)

Veno-occlusive disease of the liver (VOD) is an uncommon, early complication of hematopoietic cell transplantation (HCT) that is associated with significant mortality.

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Calculate VOD Risk

This calculator will provide a risk score to identify patients at high risk for veno-occlusive disease (VOD). Please select an option from each of the items below for the risk score to display.

Age at the time of transplant;
Age Range: <1 to 80 years. Age

Karnofsky/Lansky Score

Sirolimus used in GVHD prophylaxis Sirolimus Use

Hepatitis Serology Hepatitis B/C Status

Conditioning Regimen

Disease status at the time of transplant;
ALL - Acute Lymphoblastic Leukemia;
AML - Acute Myeloid Leukemia;
CML - Chronic Myeloid Leukemia;
NHL - Non-Hodgkin Lymphoma; Disease

Probability of developing VOD by day 100:

*Patients who received syngeneic twin transplants, did not provide signed informed consent, had inadequate follow-up, or received defibrotide as prophylaxis were not included in this study.