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Disease Risk Index (DRI) Assignment Tool

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About the Disease Risk Index (DRI)

The Disease Risk Index (DRI) is a validated tool to categorize groups of patients undergoing allogeneic stem cell transplantation (HCT) for hematologic malignancy by disease risk. It is intended for research purposes to stratify patients in broad disease risk categories for retrospective or prospective studies.

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The DRI considers only disease-related parameters (i.e., disease, stage and, for some diseases, cytogenetics) and was developed only for the primary outcome of overall survival after HCT.

It does not consider patient-related variables such as age and co-morbidities and, therefore, is NOT intended to give an accurate prognosis for individual patients.

The DRI was developed using data in adult patients with hematologic malignancies and is not yet validated for pediatric patients.

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